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Clinical trials

An in vitro study on antimicrobial effect of metallic silver colloidal against multispecies oral biofilm

Ions of silver (Ag+) are toxic to microorganisms, while metallic silver is inert in the presence of human tissues. Colloidal silver has been reported to show strong bactericidal activity on single species bacteria in suspension. Bacteria in biofilms have much higher resistance against antimicrobial agents than those in planktonic form, which makes infections more difficult to control.

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Antibiotic metal constructs to combat bacteria resistance

The pathogenic microorganisms cause significant concerns in hospitals and food storage all over the world. Currently antibiotics such as vancomycin, colistin and gentamicin are used to treat bacterial infections; however, there has been an alarming rise in the numbers of multi-drug resistant (MDR) bacteria that are resistant to most antibiotics.

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Improvement of antibiotic biopotency by complexing them with metal cations

There is an urgent demand for antimicrobial agents effective against multi-drug infections, and this rise and spread of resistant bacteria is a serious threat for health systems across the globe.

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Three samples prepared on 15/11/14 and marked B: 24hr, V: 36hr & QR: 48hr

History of three samples prepared on November 15, 2014 and marked B: 24 hours, V: 36 hours and QR: 48 hours respectively.

Details: Tested at Griffith University on Malvern Zeta Sizer 

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Enhanced antibiotic activity through complexation with metal ions

The growing problem of multi-drug resistant bacteria reduces the efficacy of antibacterial agents requiring alternative solutions to be developed. Some metal ions are known to provide antimicrobial effects and have previously been shown to be effective on open wounds and injured skin where uncontrolled micro-organism growth can delay the normal process of wound healing. An effective antibacterial agent is required to improve the wound healing process in order to avoid open wound complications for patients.

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Colloidal Silver As An Antiseptic

So often there is a singular lack of pharmacognosy – literally knowing your drug – when procuring, or even preparing, an antiseptic ‘colloidal silver’ (CS) preparation.

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Clinical Trials